Jarisch-Herxheimer reaction following penicillin treatment of early congenital syphilis.

ever, as an aftermath of the second world war there was a marked increase in the incidence of early acquired syphilis which reached its peak in the year 1946. Not unexpectedly, it resulted in a steep rise in the number of congenital syphilis cases in 1948 and 1949, followed by a gradual fall in the ensuing years to a low level in 1952 (Morton, 1954). Earlier communications on penicillin treatment of congenital syphilis, particularly from the U.S.A.,